Morphological and morphometric characteristics of the subcompensated dolichocolon

Chronic constipation is one of the most urgent problems in modern coloproctology and observed 14–16% population developed countries. The causes chronic vary widely from functional to organic. latter include various variants dolichocolon, which occur 16% cases. aim study was give a morphological quantitative characteristic subcompensated dolichocolon based on morphogenesis changes, compared with histologically normal colon. Material methods . Colon tissue samples 15 people were used, divided into two groups. first, control group consisted 5 sectional cases morphologically colon wall. second represented by surgical material 10 patients dolichocolon. Observation groups representative sex age. Results In group, thickness mucosa wall statistically significantly (p=0.034) reduced 1.06 times, indicates atrophy; submucosal layer increases 1.55 times due edema foci sclerosis (p=0.0001); muscle 1.16 (p=0,0003), because working hypertrophy compensatory hyperplasia smooth cells; at same time, number nerve cells Auerbach's plexuses decreases 1.59 (p=0,0001), will lead atrophy decrease its evacuator-motor function; average area lymphoid follicles 1.35 (p=0,003) percentage secondary 8 consequence congestion intestinal contents activation apparatus. Conclusion Morphological signs changes cellular elements neuromuscular apparatus begin form stage requires new objective clinical indications for treatment order prevent development decompensation patients’ general condition severe complications.